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Our missions
Frédéric Saudou, unit director
The aim of ours Unit is to share and use complementary skills and mode of thinking in the fields of neurobiology and cancer, to go back and forth between the mechanisms involved in the deregulation of apoptosis, proliferation, differentiation and migration in 3 cellular systems:
neurons, lymphocytes, breast epithelial cells and to identify common regulatory mechanisms in normal and pathological situations (neurodegenerative diseases such as Huntington's disease, breast cancer and lymphoid leukemia/lymphoma).
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Publications
ISG15 Modulates Development of the Erythroid Lineage. PLoS One. 2011
A family of protein-deglutamylating enzymes associated with neurodegeneration. Cell. 2010
Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis.
Neuron. 2010
Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells. Cancer Res. 2010
Postes à pourvoir/ positions available
Position immediately available in team of AYRAULT:
The candidates should be international (non-French citizen). Ideally the candidate should have a strong experience in mouse work, biochemistry and cellular biology.
A postdoctoral Fellowship for a period of 12 months is available. In the meantime, the applicant will have the opportunity to pursue in the laboratory by applying for postdoctoral fellowships. The laboratory will help and support applications.
To apply highly motivated candidates should submit a CV to Olivier Ayrault: olivier.Ayrault@curie.fr
Postes à pourvoir/ positions available
- Postdoctoral position (in team of O. Ayrault)
Séminaires/ Seminars
16/05/2012
Laura Attardi
from Department of Radiation and Cancer Biology, Standford University, USA
Title: "Deconstructing p53 Pathways in vivo Using Mouse Models"
16/05/2012
Rob Martiensen
from Cold Spring Harbor Laboratory, NY 11724, USA
Title: "Replication-coupled silencing and spreading with RNAi"

